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. Author manuscript; available in PMC: 2014 Dec 31.
Published in final edited form as: Mol Immunol. 2013 Aug 1;56(4):423–433. doi: 10.1016/j.molimm.2013.06.008

Figure 7. Inhibition of wnt signaling does not affect CTL memory programming.

Figure 7

Sorted OT1 cells were stimulated for 3 days with 3SI in the presence or absence of ICG-100 at different concentrations (0.1–10 µM). (A) Fold expansion of CTLs 3 days after in vitro stimulation was calculated according to original input. (B) Expression of activation related molecules in CTLs cells at day 3 after stimulation. (C) Activated OT1 cells were then transferred into naïve B6 mice at 106/mouse 3 days after stimulation. OT1 cells in blood 60 days after transfer. (D) Representative plots of memory OT1 cells from (C) at day 60 after transfer. Asterisks indicate statistical significance. *, P < 0.05; **, P < 0.01; ***, P < 0.001. NS: not significant.