Figure 2. Transgenic mice over-expressing SOD1 or catalase were protected from LPMI at early but not late periods of reperfusion.
(a). SOD1 tg mice (n = 4/group/time point) and WT littermates (n = 3/group/time point) were subjected to 1 hour of ischemia followed by reperfusion times of 1, 3 or 24 hours. (b). catalase tg mice (n = 5/group/time point) and WT littermates (n=5 /group/time point, except for 24 hrs where n=3) were subjected to 1 hour of ischemia followed by reperfusion times of 1, 3 or 24 hours. LPMI measurement and AAR were determined as described in Figure 1. * indicates P<0.05 compared with WT control at same time point.