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. Author manuscript; available in PMC: 2014 Sep 1.
Published in final edited form as: Stem Cells. 2013 Sep;31(9):2024–2030. doi: 10.1002/stem.1391

Figure 1. CD24 and CD44 are expressed in the stem cell zone of the human intestinal epithelium.

Figure 1

Epithelial expression of CD44 is restricted to the basolateral membranes of crypt cells (A, C, & E), with no expression in villus epithelium (B & D). CD24 is also restricted to the crypt, but is expressed on the apical membrane of epithelial cells (F & H, arrow). A subset of crypt-based epithelial cells expresses high levels of cytoplasmic CD24 (G & I, arrows). CD326 (EpCAM) is expressed throughout both the crypt and villus, but remains restricted to epithelial cells (J–L). Scale bars represent 50μm.