Figure 2. CD24−/CD44+ and CD24+/CD44+ intestinal epithelial cells are enriched for active and reserve/facultative markers, respectively.
CD24−/CD44+ cells are significantly enriched for active IESC markers (A) LGR5 and (B) OLFM4, while CD24+/CD44+ cells exhibit enrichment for (C) HOPX, which is associated with reserve/facultative IESCs. Letters a–d above each bar indicate data points that are statistically different from each other (p < 0.05).