Table 1.

General characteristics of eNOS^+/+ and eNOS^−/− mice

Treatment	Week 6
	eNOS+/+			eNOS−/−
	Normal	Diabetes+vehicle	Diabetes+BEC	Normal	Diabetes+vehicle	Diabetes+BEC
	Animal #	5	6	8	4	8	8
Body Weight (g)	25±1	20±1 a	25±1	28±1	21±1 b	23±1
Blood Glucose (mg/dL)	149±2 c	499±17	434±27	198±14 d	483.±12	473±23
SBP (mmHg)	136±3	130±4	135±7	148±4.227 e	150±4	147±5
Kidney/Body Weight (mg/g)	0.59±0.02	0.97±0.09 f	0.66±0.06	0.58±0.05 g	0.82±0.07	0.72±0.05
% Fluid	7.04±0.02	5.95±0.17	6.69±0.80	6.63±0.19	5.56±0.271	5.54±0.22
Plasma BUN (mg/dL)	23±3.02	33.83±4.74 h	26±1.08	30.25±1.65 i	43.22±4.51	41.25±3.83
Plasma Creatinine (mg/dL)	0.14±0.02	0.29±0.02 j	0.12±0.021	0.17±0.09 k	0.35±0.04	0.41±0.11

Data are mean±SEM; SBP: Systolic blood pressure; BUN: Blood urea nitrogen

^aP<0.01 compared to eNOS^+/+ normal and diabetes+BEC groups.

^bP<0.01 compared to eNOS^−/− normal group.

^cP<0.01 compared to eNOS^+/+ diabetes+vehicle and diabetes+BEC groups.

^dP<0.01 compared to eNOS^−/− diabetes+vehicle and diabetes+BEC groups.

^eP<0.05 compared to eNOS^+/+ normal group.

^fP<0.05 compared to eNOS^+/+ normal and diabetes+BEC groups.

^gP<0.05 compared to eNOS^−/− diabetes+vehicle and diabetes+BEC groups.

^hP<0.05 compared to eNOS^+/+ normal and diabetes+BEC groups.

ⁱP<0.05 compared to eNOS^−/− normal and diabetes+BEC groups.

^jP<0.05 compared to eNOS^+/+ normal and diabetes+BEC groups.

^kP<0.05 compared to eNOS^−/− normal and diabetes+BEC groups.