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Scheme of synthesis
DCM is dichloromethane, DCC is N,N-dicyclohexylcarbodiimide. Where, R-COOH is NSAID and R’-H2 is sulfonamide. 3a, R=ibuprofen and R’=suphamethoxazole; 3b, R=ibuprofen and R’=suphanilamide; 3c, R=diclofenac and R’=suphamethoxazole; 3d, R=diclofenac and R’=suphanilamide; 3e, R=flurbiprofen and R’=suphamethoxazole; 3f, R=flurbiprofen and R’=suphanilamide;
