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. 2013 Aug 13;27(5):394–405. doi: 10.7555/JBR.27.20120123

Fig. 6. Mean plasma concentration-time profiles of paclitaxel (20 mg/kg) following i.v. administration in Sprague-Dawley rats (200±40 g).

Fig. 6

(-▪-▪-) control; (-▴-▴-) virapamil (a known substrate of CYP 450 3A and inhibitor of P-gp) pretreated group, (-•-•-) atRA pretreated rats. Each point represents the mean±SD (n = 6).