Table 1. Linear regression and statistical parameters of paclitaxel from rats plasma and in cell line culture (n = 5).

Linearity range (ng/mL)		Regression data			Sa	Sb	LOD (ng/mL)	LLOQ (ng/mL)
		A	b	r2
Solution	25-2800	10.715	25.361	0.9994	1.107	1.387	10	45
Plasma	50-2800	10.092	91.735	0.9996	0.987	2.193	10	45
Cell culture	50-2800	6.5876	83.433	0.9996	1.023	1.543	15	50

a= Slope; b= Intercept; r²=Correlation coefficient; S_a =Standard deviation of intercept; S_b =Standard deviation of slope; LOD = Limit of detection; LLOQ= Lower limit of quantitation. Each standard curve was generated on 3 consecutive days distributed evenly across the linearity range. Values are reported as mean±SD of three calibration curves.