Skip to main content
. 2013 May 10;27(5):406–420. doi: 10.7555/JBR.27.20120114

Fig. 2. Entire immunization schedule.

Fig. 2

A: C57BL/6 mice were injected intramuscularly three times at 3-week intervals in both quadriceps muscles with 100 µg of plasmid DNA and sacrificed at 3 weeks after the last plasmids DNA vaccination alone or at 4 weeks after infection with M. tuberculosis H37Rv via the airway (the DNA group). B: The mice at 3 weeks after the last plasmids DNA injection were conduced through intranasal administration of the mixed ESAT-6 epitope-peptides (Ags) once a week for 2 weeks, and then parts of the mice were sacrificed or infected with M. tuberculosis H37Rv via the airway the DNA/Ags group. Moreover, these mice post M. tuberculosis H37Rv challenge for 4 weeks were sacrificed.