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Graphs illustrating the percentage of NF- (gray bars) and CR- (white bars) immunolabeled dystrophic neurites associated with fibrillar Aβ plaques at the three zones in AD, preclinical AD, APP/PS1, and Tg2576 transgenic mice, respectively (±SEM). There are significantly more dystrophic NF+ neurites traversing the Aβ plaque core, edge, and periphery than CR+ dystrophic neurites within all case types (*p < 0.05, t-test).
