TABLE 1.

Individual differences on ATL-PPI effects for guilt versus indignation irrespective of group

Between-subject covariate of interest	Interpretation	Hemisphere	Anatomical description	Brodmann area	MNI coordinates			t-value
					x	y	z
Positive effect of interaction score (VALENCE × CONCEPT)	Increased guilt-selective coupling in individuals with relative noninterdependence of conceptual generalization and valence biases	R	Anterior dorsolateral prefrontal cortex	46	44	36	8	4.59∗
		R	Septal part of nucleus accumbens	–	8	6	−4	3.34∗∗
Negative effect of interaction score (VALENCE × CONCEPT)	Increased guilt-selective coupling in individuals with high interdependence of conceptual generalization and valence biases	L	Middle anterior temporal cortex	21	−58	−4	−2	4.31∗
		L	Superior anterior temporal cortex	22	−58	0	−6	3.36∗∗
Positive effect of conceptual score (S_AG – O_AG)	Increased guilt-selective coupling in S_AG-selective conceptual overgeneralizers	R	Thalamus/hypothalamus	–	8	−6	2	3.39∗
		R	Anterior dorsolateral prefrontal cortex	46	42	38	10	3.43∗
Negative effect of conceptual score (S_AG – O_AG)	Increased guilt-selective coupling in S_AG-selective conceptual overdifferentiators	L	Middle anterior temporal cortex	21	−58	−4	−22	4.96∗
		L	Parahippocampal gyrus	35	−18	−8	−28	4.54∗

Notes: Only regions surviving inclusive masking with guilt versus null are reported. No other regions survived an uncorrected threshold of p = .005 (extent threshold of 4 voxels) and a voxel- or cluster-level p = .05 over the whole brain or our a priori ROIs. ∗Survived voxel-wise FWE-correction over tier 1 ROI; ∗∗Survived voxel-wise FWE-correction over tier 2 ROI. S_AG = self-agency condition, O_AG = other-agency condition, between-subject covariates in all models were group (MDD/control), the main effects of conceptual (CONCEPT) and valence (VALENCE) difference scores (S_AG – O_AG), and their interaction score (VALENCE × CONCEPT).