Table 2.
Effect of treatment with melatonin on brain antioxidant status in ovariectomized and Al-intoxicated ovariectomized rats
| Groups | Parameters | ||
|---|---|---|---|
| TAC (mmol/mg protein) | SOD (U/mg protein) | CAT (U/mg protein) | |
| Gonad intact control | 14.20 ± 0.81 | 2.81 ± 0.18 | 5.79 ± 0.31 |
| Ovx control | 8.86 ± 0.43a (−37.62 %) | 2.06 ± 0.19a (−26.60 %) | 4.95 ± 0.29 (−14.55 %) |
| Ovx + melatonin | 10.57 ± 0.53b (19.30 %) | 2.50 ± 0.15 (21.21 %) | 5.56 ± 0.29 (12.32 %) |
| Al-intoxicated control | 6.33 ± 0.35b (−28.55 %) | 1.80 ± 0.17 (−12.72 %) | 4.16 ± 0.26 (−15.95 %) |
| Ovx + Al + melatonin | 9.91 ± 0.51c (56.63 %) | 2.21 ± 0.12 (22.91 %) | 5.28 ± 0.31c (27.09 %) |
Data are represented as Mean ± SE (10 rats/group)
Ovx ovariectomized
asignificant change at p < 0.05 in comparison with gonad intact control group
bsignificant change at p < 0.05 in comparison with ovariectomized control group
csignificant change at p < 0.05 in comparison with Al-intoxicated control group
(%) percent of difference with respect to corresponding control value