(a) Cells were treated for 24, 48, and 72 hours with GSK461364A at IC75 concentration. At the end of the treatment, cells were stained by annexin V and propidium iodide and analyzed with FACS. **p<0.01, ***p<0.001. (b) Caspase 3 detection by Western blot after 72 hours of treatment with GSK461364A at IC75 concentration. FACS, fluorescence-activated cell sorting.