Figure 3. Effects of exercise on pilocarpine-induced seizure susceptibility in SwLo and SwHi rats.
After the forced swim test, rats were returned to their sedentary or exercise cages. One week later, seizure susceptibility was tested. Shown is the mean ± SEM latency to first behavioral seizure (Panels A & B), latency to limbic motor seizure (Panels C & D), and percent of rats progressing to status epilepticus (Panels E & F; raw number of rats progressing to status epilepticus over the total tested are shown above each bar) following administration of pilocarpine (380 mg/kg i.p.). *P<0.05, **p<0.01, ***p<0.001 compared to sedentary for that rat line. N=12-14 rats per group.