. Author manuscript; available in PMC: 2013 Sep 26.

Published in final edited form as: Neurobiol Dis. 2012 Mar 5;46(3):625–634. doi: 10.1016/j.nbd.2012.02.012

Table 3.

Mean (SD) of key variables for the longitudinal sample by disease progression group at the first visit.

CAP group

Variable	Control	Low	Medium	High	Test
Striatum	1.10 (0.13)	1.02 (0.13)	0.93 (0.16)	0.81 (0.14)	F(3,47) = 11.73^***
TMS	2.90 (2.49)	0.75 (1.49)	4.16 (4.68)	9.35 (6.74)	F(3,74) = 10.58^***
FAS	25 (0)	25 (0)	24.84 (0.37)	24.74 (0.68)	F(3,74) = 1.48
SDMT	56.45 (5.77)	59.00 (11.74)	51.89 (13.50)	44.87 (10.55)	F(3,74) = 6.87^***
BDI	4.60 (5.58)	4.12 (5.00)	8.37 (8.78)	9.52 (10.24)	F(3,74) = 1.86
Education	16 (2.15)	14.62 (2.39)	14.42 (2.97)	15 (2.92)	F(3,74) = 1.23
Entry age	42.49 (9.09)	38.04 (8.55)	40.79 (9.63)	45.74 (8.63)	F(3,74) = 2.17
Sex	0.55	0.5	0.63	0.52	χ²(3) = 0.74
Diagnosis	0	0	0.21	0.39	χ²(3) = 13.52^**

Note. Striatum=ratio of striatal volume to total brain volume×100; TMS = Total Motor Score; FAS = Functional Assessment; SDMT = Symbol Digit Modalities Test; BDI = Beck Depression Inventory; Sex = proportion of males; Diagnosis = proportion who eventually phenoconverted.

^**

p<0.01.

^***

p<0.001.