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. 2013 Aug 15;72(4):897–908. doi: 10.1007/s00280-013-2249-z

Table 4.

Characteristics of primary leukemia cells for in vitro studies

Patient samples Diagnosis Disease status Cytogenetics FLT3 NPM1 Source % Blast
AML 01 AML arising from MDS Status post-azacitidine for MDS t(3;21), +8 WT ND BM 8
AML 02 AML post-ET Untreated

Del (20q),

t(1;19) (q25;q13.3)

WT WT BM 21
ALL 03 ALL First relapse Normal ND ND PB 60
AML 04 AML Primary refractory Normal WT WT BM 25
AML 05 AML Untreated Inv(16) WT WT BM 61
AML 06 AML Untreated Normal D835 MUT PB 90
AML 07 AML Untreated Normal ITD ND BM 78
AML 08 AML Untreated Normal WT MUT BM 73

FLT3 FMS-like tyrosine kinase 3, NMP1 nucleophosmin 1, MDS myelodysplastic syndrome, ET essential thrombocytosis, WT wild type, ND not done, ITD internal tandem duplication, MUT mutated, BM bone marrow, PB peripheral blood