Table 4.
Patient samples | Diagnosis | Disease status | Cytogenetics | FLT3 | NPM1 | Source | % Blast |
---|---|---|---|---|---|---|---|
AML 01 | AML arising from MDS | Status post-azacitidine for MDS | t(3;21), +8 | WT | ND | BM | 8 |
AML 02 | AML post-ET | Untreated |
Del (20q), t(1;19) (q25;q13.3) |
WT | WT | BM | 21 |
ALL 03 | ALL | First relapse | Normal | ND | ND | PB | 60 |
AML 04 | AML | Primary refractory | Normal | WT | WT | BM | 25 |
AML 05 | AML | Untreated | Inv(16) | WT | WT | BM | 61 |
AML 06 | AML | Untreated | Normal | D835 | MUT | PB | 90 |
AML 07 | AML | Untreated | Normal | ITD | ND | BM | 78 |
AML 08 | AML | Untreated | Normal | WT | MUT | BM | 73 |
FLT3 FMS-like tyrosine kinase 3, NMP1 nucleophosmin 1, MDS myelodysplastic syndrome, ET essential thrombocytosis, WT wild type, ND not done, ITD internal tandem duplication, MUT mutated, BM bone marrow, PB peripheral blood