Table 4.

Comparison of the genotype frequency of the presence or absence of aspartic acid at position 57 and of glutamate at position 86 of HLA-DQ chain between patients and controls

Allele	Patients (2n = 188)	Controls (2n = 208)	P-value	OR	95% CI
β57
Asp	87 (46·2%)	97 (46·6%)
Non-Asp	101 (53·7%)	111 (53·3%)	NS	–	–
β86
Glu	57 (30·3%)	91 (43·7%)
Non-Glu	131 (69·6%)	117 (56·2%)	0·008	1·79	1·16–2·77
Genotype	(n = 94)	(n = 104)
β57
Asp/Asp	27 (28·7%)	27 (25·9%)	0·782	1·149	0·585–2·255
Non-Asp/Asp	33 (35·1%)	43 (41·3%)	0·45	0·767	0·413–1·419
Non-Asp/Non-Asp	34 (36·1%)	34 (32·6%)	0·715	1·166	0·621–2·189
β86
Glu/Glu	10 (10·6%)	29 (27·8%)	0·004	0·307	0·125–0·707
Non-Glu/Glu	37(39·3%)	33 (31·7%)	0·33	1·396	0·746–2·613
Non-Glu/Non-Glu	47(50%)	42 (40·3%)	0·224	1·476	0·809–2·694