Table 1.
Phenotypes of the diffuse large B-cell lymphoma (DLBCL) cell lines used in this study.
| Cell line | DLBCL type | CIITA/HLA-DR levels |
|---|---|---|
| DB | GCB | Negative/negative |
| OCI-Ly3 | ABC | Intermediate/intermediate |
| OCI-Ly7 | GCB | Intermediate/intermediate |
| OCI-Ly10 | ABC | Intermediate/negative |
| OCI-Ly19 | GCB | High/high |
| SUDHL-4 | GCB | Low/low |
| SUDHL-6 | GCB | Low/low |
| Farage | GCB | High/high |
| Toledo | GCB | Intermediate/intermediate |
Cell lines were categorized as germinal centre B cells (GCB) or activated B cells (ABC) based on gene expression profiling studies. CIITA and HLA-DR expression levels were based on the results of quantitative RT-PCR and flow cytometric analyses43