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. 2012 Aug 13;591(Pt 18):4415–4426. doi: 10.1113/jphysiol.2012.238451

Figure 2. Effects of electrically stimulated muscle contraction on fatty acid transport, and plasma membrane CD36.

Figure 2

Data are means ± SEM. Fatty acid transport was examined in giant sarcolemmal vesicles obtained from rat skeletal muscles and plasma membrane CD36 was measured in these vesicles. A, the effect of muscle contraction and recovery from muscle contraction on the rate of fatty acid transport. B, the relationship between the rate of muscle contraction and the rate of fatty acid transport. C, the relative changes in the rate of fatty acid transport and plasma membrane CD36 at the end of 30 min muscle contraction and at the end of 55 min recovery (rest = 100%). D, the effect of the CD36 inhibitor (SSO) on fatty acid transport in resting and in 30 min contracted muscle. Note that control (–SSO) and the inhibition studies were conducted on vesicles from the same pools of resting and contracting muscles as shown by the similar plasma membrane CD36 in each of these two conditions. *P < 0.05, contraction vs. rest (A–D), and contraction vs. recovery (C). **P < 0.05, 40 Hz vs. 20 Hz (B). ***P < 0.05, +SSO treatment vs.–SSO treatment in resting and contracting muscle (D). From Bonen et al. (2000); © American Society for Biochemistry and Molecular Biology.