Table 1.
Evoked changes in IC activity in response to afferent and efferent stressors
| Increased FF (P < 0.01) | Increased FF (P < 0.05) | |||||||
|---|---|---|---|---|---|---|---|---|
| Stressor | Baseline | Stress | P value | n | Baseline | Stress | P value | n |
| RV | 0.01 ± 0.01 | 0.42 ± 0.19 | P= 0.03 | 6 | 0.03 ± 0.05 | 0.44 ± 0.28 | P= 0.00 | 12 |
| LV | 0.25 ± 0.02 | 0.91 ± 0.19 | P= 0.50 | 2 | 0.15 ± 0.12 | 0.64 ± 0.33 | P= 0.12 | 4 |
| Ao Occl | 0.05 ± 0.08 | 0.98 ± 1.03 | P= 0.00 | 18 | 0.04 ± 0.08 | 0.89 ± 1.01 | P= 0.00 | 20 |
| IVC Occl | 0.12 ± 0.27 | 0.59 ± 0.87 | P= 0.00 | 12 | 0.09 ± 0.23 | 0.46 ± 0.75 | P= 0.00 | 17 |
| RCV | 0.06 ± 0.10 | 0.73 ± 0.56 | P= 0.00 | 17 | 0.05 ± 0.09 | 0.57 ± 0.56 | P= 0.00 | 23 |
| LCV | 0.13 ± 0.24 | 0.57 ± 0.58 | P= 0.00 | 12 | 0.11 ± 0.22 | 0.51 ± 0.56 | P= 0.00 | 14 |
| RSS | 0.14 ± 0.13 | 0.71 ± 0.45 | P= 0.00 | 10 | 0.15 ± 0.30 | 0.48 ± 0.50 | P= 0.00 | 23 |
| LSS | 0.16 ± 0.17 | 0.66 ± 0.37 | P= 0.00 | 14 | 0.19 ± 0.20 | 0.60 ± 0.36 | P= 0.00 | 21 |
| MNS | 0.18 ± 0.90 | 1.43 ± 1.90 | P= 0.00 | 35 | 0.15 ± 0.82 | 1.24 ± 1.79 | P= 0.00 | 42 |
| LAD CAO | 0.18 ± 0.12 | 0.78 ± 0.75 | P= 0.03 | 6 | 0.26 ± 0.23 | 0.66 ± 0.56 | P= 0.00 | 14 |
| Decreased FF (P < 0.01) | Decreased FF (P < 0.05) | |||||||
| RV | 4.03 ± 0.00 | 0.12 ± 0.00 | P= 1.00 | 1 | 2.67 ± 1.92 | 0.12 ± 0.00 | P= 0.50 | 2 |
| LV | 0.70 ± 0.52 | 0.26 ± 0.04 | P= 0.50 | 2 | 0.67 ± 0.37 | 0.22 ± 0.08 | P= 0.25 | 3 |
| Ao Occl | 1.54 ± 0.93 | 0.51 ± 0.63 | P= 0.03 | 6 | 1.33 ± 0.89 | 0.44 ± 0.57 | P= 0.01 | 8 |
| IVC Occl | 1.19 ± 1.39 | 0.12 ± 0.15 | P= 0.06 | 5 | 0.79 ± 1.18 | 0.08 ± 0.13 | P= 0.01 | 8 |
| RCV | 0.74 ± 0.53 | 0.15 ± 0.19 | P= 0.02 | 7 | 0.67 ± 0.53 | 0.14 ± 0.18 | P= 0.01 | 8 |
| LCV | 0.51 ± 0.40 | 0.12 ± 0.16 | P= 0.03 | 6 | 0.53 ± 0.37 | 0.15 ± 0.18 | P= 0.02 | 7 |
| RSS | 2.00 ± 2.44 | 1.29 ± 2.17 | P= 0.25 | 3 | 1.53 ± 2.20 | 0.97 ± 1.88 | P= 0.12 | 4 |
| LSS | 1.54 ± 1.43 | 0.48 ± 0.55 | P= .12 | 4 | 1.00 ± 1.13 | 0.37 ± 0.43 | P= 0.01 | 8 |
| MNS | 0.79 ± 0.21 | 0.08 ± 0.10 | P= .25 | 3 | 0.51 ± 0.35 | 0.07 ± 0.09 | P= 0.03 | 6 |
| LAD CAO | 0.64 ± 0.54 | 0.17 ± 0.29 | P= 0.01 | 8 | 0.48 ± 0.49 | 0.13 ± 0.24 | P= 0.00 | 12 |
IC neuronal activity (mean ± SD) at baseline and in response to indicated stressors (see Abbreviations). Responses are subdivided based upon evoked increases in activity (upper rows) and decreased activity (lower rows). P values were derived based on analysis described in Appendix and Fig. 2. Based on that analysis, responses are subdivided based upon evoked responses with P < 0.01 (left panels) and P < 0.05 (right panels). FF, firing frequency; Ao, aortic; Occl, occlusion.