Table 2.
Relationship among sialography (Rubin–Holt stage), labial salivary gland biopsy (Greenspan's grade) and presence of αREG.
| αREG | P-value | |||
|---|---|---|---|---|
| (+) | (−) | |||
| Sialography (Rubin–Holt stage) | ||||
| 0 | Normal | 20% (2/10) | 22% (16/72) | n.s. |
| 1 | Punctate | 10% (1/10) | 21% (15/72) | n.s. |
| 2 | Globular | 0·0% (0/10) | 18% (13/72) | n.s. |
| 3 | Cavitary | 20% (2/10) | 32% (23/72) | n.s. |
| 4 | Destructive | 50% (5/10) | 6·9% (5/72) | 0·000097 |
| Labial salivary gland biopsy (Greenspan's grade) | ||||
| 0 | 0·0% (0/12) | 1·7% (1/59) | n.s. | |
| 1 | 0·0% (0/12) | 3·4% (2/59) | n.s. | |
| 2 | 8·3% (1/12) | 6·8% (4/59) | n.s. | |
| 3 | 8·3% (1/12) | 14% (8/59) | n.s. | |
| 4 | 42% (5/12) | 41% (24/59) | n.s. | |
| 5 (+germinal centres)† | 42% (5/12) | 34% (20/59) | n.s. | |
Not significant (n.s.): P ≥ 0·05.
†
In the grade 4 group, we classified ‘grade 5’ in which germinal centres were found in the histopathology.