Fig. 6.

Toll-like receptor (TLR)-4-induced CD83 and cytokine expression in rhesus (n = 6) versus human (n = 4) peripheral blood plasmacytoid dendritic cells (pDC), myeloid dendritic cells (mDC) and monocytes. For each subset the percentage of cells expressing CD83 (pDC and mDC) or CD80 (monocytes), interferon (IFN)-α, interleukin (IL)-12p40 or tumour necrosis factor (TNF)-α after 8 h stimulation with 1 μg/ml lipopolysaccharide is shown (filled symbols); background expression as observed in cultured non-stimulated cells (open symbols) was not subtracted. *P < 0·05.