Table 1.
Age-associated mortality during acute pancreatitis
|
Young (4–5 months old) Dead/Total |
Middle-aged (12–13 months old) Dead/Total |
Aged (23–25 months old) Dead/Total |
|
|---|---|---|---|
| Survival test1 | 0/10 | 0/10 | 1/10 |
| 24 h time point study2 | 0/39 | 0/10 | 7/76 |
| Combined | 0/49 (0%) |
0/20 (0%) |
8/86## (9.3%) |
1
For survival test, all mice were monitored for 2 weeks; one aged mouse died within 24 hours.
2
For 24 h time point study, all mice were sacrificed for biochemical analysis 24 h after the final injection with caerulein, and mortality during this period of time was recorded.
##
p<0.01 comparing aged vs. young and middle-aged mice.