| Peds |
Peds-001A |
In infants (<1 year, not including newly born) in cardiac arrest (prehospital [OHCA], in-hospital [IHCA]) (P), does the use of AEDs (I) compared with standard management (which does not include use of AEDs) (C), improve outcomes (eg. termination of rhythm, ROSC, survival) (O)? |
AEDs in children less than 1 yr |
Reylon A. Meeks |
http://circ.ahajournals.org/site/C2010/Peds-001A.pdf |
| Peds |
Peds-001B |
In infants (<1 year, not including newly born) in cardiac arrest (prehospital [OHCA], in-hospital [IHCA]) (P), does the use of AEDs (I) compared with standard management (which does not include use of AEDs) (C), improve outcomes (eg. termination of rhythm, ROSC, survival) (O)? |
AEDs in children less than 1 yr |
Antonio Rodriguez-Nunez |
http://circ.ahajournals.org/site/C2010/Peds-001B.pdf |
| Peds |
Peds-002A |
For infants and children in cardiac arrest, does the use of a pulse check (I) vs. assessment for signs of life (C) improve the accuracy of diagnosis of pediatric CPA (O)? |
Pulse check accuracy |
Aaron Donoghue, James Tibballs |
http://circ.ahajournals.org/site/C2010/Peds-002A.pdf |
| Peds |
Peds-003 |
During cardiac arrest in infants or children (P), does the presence of family members during the resuscitation (I) compared to their absence (C) improve patient or family outcome measures (O)? |
Family presence |
Douglas S. Diekema |
http://circ.ahajournals.org/site/C2010/Peds-003.pdf |
| Peds |
Peds-004 |
In infants and children with respiratory failure who undergo endotracheal intubation (prehospital [OHCA], in-hospital [IHCA]) (P), does the use of devices (eg. CO2 detection device, CO2 analyzer or esophageal detector device) (I) compared with usual management (C), improve the accuracy of diagnosis of airway placement (O)? |
Verification of airway placement |
Diana G. Fendya, Monica Kleinman |
http://circ.ahajournals.org/site/C2010/Peds-004.pdf |
| Peds |
Peds-005A |
In pediatric patients with cardiac arrest (prehospital [OHCA] or in-hospital [IHCA]) (P), does the use of end-tidal CO2 (I), compared with clinical assessment (C), improve accuracy of diagnosis of a perfusing rhythm (O)? |
End-tidal CO2 to diagnose perfusing rhythm |
Arno Zaritsky |
http://circ.ahajournals.org/site/C2010/Peds-005A.pdf |
| Peds |
Peds-005B |
In pediatric patients with cardiac arrest (prehospital [OHCA] or in-hospital [IHCA]) (P), does the use of end-tidal CO2 (I), compared with clinical assessment (C), improve accuracy of diagnosis of a perfusing rhythm (O)? |
End-tidal CO2 to diagnose perfusing rhythm |
Anne-Marie Guerguerian |
http://circ.ahajournals.org/site/C2010/Peds-005B.pdf |
|
| Peds |
Peds-006B |
In pediatric patients in clinical cardiac arrest (prehospital [OHCA] or in hospital [IHCA]) (P), does the use of a focused echocardiogram (I) compared with standard assessment, assist in the diagnosis of reversible causes of cardiac arrest? |
Methods to diagnose perfusing rhythm |
Christoph B. Eich, Faiqa A. Qureshi |
http://circ.ahajournals.org/site/C2010/Peds-006B.pdf |
| Peds |
Peds-007 |
In children requiring emergent intubation (prehospital, in-hospital) (P), does the use of cuffed ETTs (I) compared with uncuffed ETTs (C) improve therapeutic endpoints (eg, oxygenation and ventilation) or reduce morbidity or risk of complications (eg, need for tube change, airway injury, aspiration) (O)? |
Cuffed vs uncuffed ETTs |
Ashraf Coovadia |
http://circ.ahajournals.org/site/C2010/Peds-007.pdf |
| Peds |
Peds-008 |
In children requiring assisted ventilation (prehospital, in-hospital) (P), does the use of bag-valve-mask (I) compared with endotracheal intubation (C) improve therapeutic endpoints (oxygenation and ventilation), reduce morbidity or risk of complications (eg, aspiration), or improve survival (O)? |
BVM vs intubation |
Dominique Biarent |
http://circ.ahajournals.org/site/C2010/Peds-008.pdf |
| Peds |
Peds-009 |
In pediatric patients in cardiac arrest (prehospital [OHCA] or in-hospital [IHCA]) (P), does the use of supraglottic airway devices (I) compared with bag-valve-mask alone (C), improve therapeutic endpoints (eg, ventilation and oxygenation), improve quality of resuscitation (eg, reduce hands-off time, allow for continuous compressions), reduce morbidity or risk of complications (eg, aspiration) or improve survival (O)? |
Supraglottic airway devices |
Robert Bingham |
http://circ.ahajournals.org/site/C2010/Peds-009.pdf |
| Peds |
Peds-010A |
For infants and children who have ROSC after cardiac arrest (P), does the use of induced hypothermia (I) compared with normothermia (C) improve outcome (survival to discharge, survival with good neurologic outcome) (O)? |
Induced hypothermia after ROSC |
Robert Hickey |
http://circ.ahajournals.org/site/C2010/Peds-010A.pdf |
| Peds |
Peds-010B |
For infants and children who have ROSC after cardiac arrest (P), does the use of induced hypothermia (I) compared with normothermia (C) improve outcome (survival to discharge, survival with good neurologic outcome) (O)? |
Induced hypothermia after ROSC |
James S. Hutchison |
http://circ.ahajournals.org/site/C2010/Peds-010B.pdf |
| Peds |
Peds-011B |
In infants and children with cardiac arrest from a non-asphyxial or asphyxial cause (excluding newborns) (prehospital [OHCA] or in-hospital [IHCA]) (P), does the use of another specific C:V ratio by laypersons and HCPs (I) compared with standard care (15:2) (C), improve outcome (eg, ROSC, survival) (O)? |
Compression ventilation ratio |
Robert Bingham, Robert Hickey |
http://circ.ahajournals.org/site/C2010/Peds-011B.pdf |
| Peds |
Peds-012A |
In infants and children (not including newborns) with cardiac arrest (out-of-hospital and in-hospital) (P), does the use of compression-only CPR (I) as opposed to standard CPR (ventilations and compressions) (C), improve outcome (O) (eg, ROSC, survival)? |
Compression only CPR |
Robert A. Berg, Dominique Biarent |
http://circ.ahajournals.org/site/C2010/Peds-012A.pdf |
| Peds |
Peds-013A |
In pediatric patients with cardiac arrest (prehospital [OHCA] or in-hospital [IHCA]) and a secure airway (P), does the use of a specific minute ventilation (combination of respiratory rate and tidal volume) depending on the etiology of the arrest (I) as opposed to standard care (8–10 asynchronous breaths per minute) (C), improve outcome (O) (eg. ROSC, survival)? |
Etiology specific minute ventilation |
Monica Kleinman |
http://circ.ahajournals.org/site/C2010/Peds-013A.pdf |
| Peds |
Peds-013B |
In pediatric patients with cardiac arrest (prehospital [OHCA] or in-hospital [IHCA]) and a secure airway (P), does the use of a specific minute ventilation (combination of respiratory rate and tidal volume) depending on the etiology of the arrest (I) as opposed to standard care (8–10 asynchronous breaths per minute) (C), improve outcome (O) (eg. ROSC, survival)? |
Etiology specific minute ventilation |
Naoki Shimizu |
http://circ.ahajournals.org/site/C2010/Peds-013A.pdf |
| Peds |
Peds-014 |
In pediatric patients in cardiac arrest (prehospital [OHCA] or in-hospital [IHCA]) (P) does the use of rapid deployment ECMO or emergency cardiopul-monary bypass (I), compared with standard treatment (C), improve outcome (ROSC, survival to hospital discharge, survival with favorable neurologic outcomes) (O)?” |
ECMO |
Marilyn Morris |
http://circ.ahajournals.org/site/C2010/Peds-014.pdf |
| Peds |
Peds-014B |
In pediatric patients in cardiac arrest (prehospital [OHCA] or in-hospital [IHCA]) (P) does the use of rapid deployment ECMO or emergency cardiopul-monary bypass (I), compared with standard treatment (C), improve outcome (ROSC, survival to hospital discharge, survival with favorable neurologic outcomes) (O)? |
ECMO |
Kate L. Brown |
http://circ.ahajournals.org/site/C2010/Peds-014B.pdf |
| Peds |
Peds-015 |
In pediatric patients in cardiac arrest, associated with or without asphyxia (prehospital [OHCA] or in-hospital [IHCA]) (P) does ventilation with a specific oxygen concentration (room air or a titrated concentration between 0.21 and 1.0) (I), compared with standard treatment (100% oxygen) (C), improve outcome (ROSC, survival to hospital discharge, survival with favorable neurologic outcome) (O)? |
Titrated oxygen vs 100% oxygen |
Robert Hickey |
http://circ.ahajournals.org/site/C2010/Peds-015.pdf |
| Peds |
Peds-016 |
In infants and children with ROSC after cardiac arrest (prehospital or in-hospital) (P), does the use of a specific strategy to manage blood glucose (eg. target range) (I) as opposed to standard care (C), improve outcome (O) (eg. survival)? |
Glucose control following resuscitation |
Duncan Macrae, Vijay Srinivasan |
http://circ.ahajournals.org/site/C2010/Peds-016.pdf |
| Peds |
Peds-017B |
In pediatric patients with cardiac arrest (pre-hospital [OHCA] or in-hospital [IHCA]) (P), does the use of any specific alternative method for calculating drug dosages (I) compared with standard weight-based dosing (C), improve outcome (eg, achieving expected drug effect, ROSC, survival, avoidance of toxicity) (O)? |
Methods for calculating drug dosages |
Ian Maconochie, Vijay Srinivasan |
http://circ.ahajournals.org/site/C2010/Peds-017B.pdf |
| Peds |
Peds-018 |
In adult and pediatric patients with cardiac arrest (pre-hospital [OHCA] or in-hospital [IHCA) (P), does the use of any specific alternative dosing regimen for epinephrine (I) compared with standard recommendations (C), improve outcome (eg. ROSC, survival to hospital discharge, survival with favorable neurologic outcome) (O)? |
Epinephrine dose |
Amelia Reis |
http://circ.ahajournals.org/site/C2010/Peds-018.pdf |
| Peds |
Peds-019 |
In pediatric patients with cardiac arrest (pre-hospital [OHCA] or in-hospital [IHCA]) due to VF/pulseless VT (P), does the use of amiodarone (I) compared with lidocaine (C), improve outcome (eg, ROSC, survival to hospital discharge, survival with favorable neurologic outcome) (O)? |
Amiodarone vs lidocaine for VF/VT |
Dianne L. Atkins |
http://circ.ahajournals.org/site/C2010/Peds-019.pdf |
| Peds |
Peds-020A |
In adult and pediatric patients with cardiac arrest (prehospital [OHCA] or in-hospital [IHCA]) (P), does the use of vasopressin or vasopressin + epinephrine (I) compared with standard treatment recommendations (C), improve outcome (eg, ROSC, survival to hospital discharge, or survival with favorable neurologic outcome) (O)? |
Vasopressin |
Elise W. van der Jagt |
http://circ.ahajournals.org/site/C2010/Peds-020A.pdf |
| Peds |
Peds-020B |
In adult and pediatric patients with cardiac arrest (prehospital [OHCA] or in-hospital [IHCA]) (P), does the use of vasopressin or vasopressin + epinephrine (I) compared with standard treatment recommendations (C), improve outcome (eg, ROSC, survival to hospital discharge, or survival with favorable neurologic outcome) (O)? |
Vasopressin |
Dominique Biarent |
http://circ.ahajournals.org/site/C2010/Peds-020B.pdf |
| Peds |
Peds-021A |
In pediatric patients with cardiac arrest (pre-hospital [OHCA] or in-hospital [IHCA]) (P), does the use of calcium (I) compared with no calcium (C), improve outcome (O) (eg. ROSC, survival to hospital discharge, survival with favorable neurologic outcome)? |
Calcium |
Allan de Caen |
http://circ.ahajournals.org/site/C2010/Peds-021A.pdf |
| Peds |
Peds-021B |
In pediatric patients with cardiac arrest (pre-hospital [OHCA] or in-hospital [IHCA]) (P), does the use of calcium (I) compared with no calcium (C), improve outcome (O) (eg. ROSC, survival to hospital discharge, survival with favorable neurologic outcome)? |
Calcium |
Felipe Martinez, Sergio Pesutic, Sergio Rendich |
http://circ.ahajournals.org/site/C2010/Peds-021B.pdf |
| Peds |
Peds-022A |
In pediatric patients with cardiac arrest due to primary or secondary VF or pulseless VT (pre-hospital [OHCA] or in-hospital [IHCA]) (P), does the use of more than one shock for the initial or subsequent defibrillation attempt(s) (I), compared with standard management (C), improve outcome (eg. termination of rhythm, ROSC, survival to hospital discharge, survival with favorable neurologic outcome) (O)? |
Single or stacked shocks |
Marc Berg |
http://circ.ahajournals.org/site/C2010/Peds-022A.pdf |
| Peds |
Peds-023A |
In pediatric patients with cardiac arrest due to primary or secondary VF or pulseless VT (pre-hospital [OHCA] or in-hospital [IHCA]) (P), does the use of a specific energy dose or regimen of energy doses for the initial or subsequent defibrillation attempt(s) (I), compared with standard management (C), improve outcome (eg. termination of rhythm, ROSC, survival to hospital discharge, survival with favorable neurologic outcome) (O)? |
Energy doses |
Jonathan R. Egan |
http://circ.ahajournals.org/site/C2010/Peds-023A.pdf |
| Peds |
Peds-023B |
In pediatric patients with cardiac arrest due to primary or secondary VF or pulseless VT (pre-hospital [OHCA] or in-hospital [IHCA]) (P), does the use of a specific energy dose or regimen of energy doses for the initial or subsequent defibrillation attempt(s) (I), compared with standard management (C), improve outcome (eg. termination of rhythm, ROSC, survival to hospital discharge, survival with favorable neurologic outcome) (O)? |
Energy doses |
Dianne L. Atkins |
http://circ.ahajournals.org/site/C2010/Peds-023B.pdf |
| Peds |
Peds-024A |
In pediatric patients with ROSC after cardiac arrest (pre-hospital [OHCA] or in-hospital [IHCA]) who have signs of cardiovascular dysfunction (P), does the use of any specific cardioactive drugs (I) as opposed to standard care (or different cardioactive drugs) (C), improve physiologic endpoints (oxygen delivery, hemodynamics) or patient outcome (eg, survival to discharge or survival with favorable neurologic outcome) (O)? |
Cardioactive drugs post resuscitation |
Allan de Caen |
http://circ.ahajournals.org/site/C2010/Peds-024A.pdf |
| Peds |
Peds-024B |
In pediatric patients with ROSC after cardiac arrest (pre-hospital [OHCA] or in-hospital [IHCA]) who have signs of cardiovascular dysfunction (P), does the use of any specific cardioactive drugs (I) as opposed to standard care (or different cardioactive drugs) (C), improve physiologic endpoints (oxygen delivery, hemodynamics) or patient outcome (eg, survival to discharge or survival with favorable neurologic outcome) (O)? |
Cardioactive drugs post resuscitation |
Mark G. Coulthard |
http://circ.ahajournals.org/site/C2010/Peds-024B.pdf |
| Peds |
Peds-025A |
In pediatric patients with in-hospital cardiac or respiratory arrest (P), does use of EWSS/response teams/MET systems (I) compared with no such responses (C), improve outcome (eg, reduce rate of cardiac and respiratory arrests and in-hospital mortality) (O)? |
METs |
Elise W. van der Jagt |
http://circ.ahajournals.org/site/C2010/Peds-025A.pdf |
| Peds |
Peds-025B |
In pediatric patients with in-hospital cardiac or respiratory arrest (P), does use of EWSS/response teams/MET systems (I) compared with no such responses (C), improve outcome (eg, reduce rate of cardiac and respiratory arrests and in-hospital mortality) (O)? |
METs |
James Tibballs |
http://circ.ahajournals.org/site/C2010/Peds-025B.pdf |
| Peds |
Peds-026A |
For intubated newborns within the first month of life (beyond the delivery room) who are receiving chest compressions (P), does the use of continuous chest compressions (without pause for ventilation) (I) vs. chest compressions with interruptions for ventilation (C) improve outcome (time to sustained heart rate >100, survival to ICU admission, survival to discharge, survival with favorable neurologic status) (O)? |
Continuous chest compressions for intubated newborns outside of DR |
Monica Kleinman |
http://circ.ahajournals.org/site/C2010/Peds-026A.pdf |
| Peds |
Peds-027A |
For newborns within the first month of life (beyond the delivery room) who are not intubated and who are receiving CPR (P), does the use of a 3:1 compression to ventilation ratio (I), compared with a 15:2 compression to ventilation ratio (C) improve outcome (time to sustained heart rate >100, survival to ICU admission, survival to discharge, discharge with favorable neurologic status) (O)? |
3:1 vs 15:2 ratio for neonates outside of DR |
Leon Chameides |
http://circ.ahajournals.org/site/C2010/Peds-027A.pdf |
| Peds |
Peds-028 |
In pediatric patients with cardiac arrest (out-of-hospital and in-hospital) (including prolonged arrest states) (P), does the use of NaHCO3 (I) compared with no NaHCO3 (C), improve outcome (O) (eg. ROSC, survival)? |
Sodium bicarbonate |
Stephen M. Schexnayder |
http://circ.ahajournals.org/site/C2010/Peds-028.pdf |
| Peds |
Peds-029 |
In infants and children in cardiac arrest (prehospital [OHCA], in-hospital [IHCA]) (P), does the use of any specific paddle/pad size/orientation and position (I) compared with standard resuscitation or other specific paddle/pad size/orientation and position) (C), improve outcomes (eg. Successful defibrillation, ROSC, survival) (O)? |
Paddle size and placement for defibrillation |
Dianne L. Atkins |
http://circ.ahajournals.org/site/C2010/Peds-029.pdf |
| Peds |
Peds-030 |
In infants and children with unstable ventricular tachycardia (pre-hospital and in-hospital) (P), does the use of any drug/combination of drugs/intervention (eg. cardioversion) (I) compared with no drugs/intervention (C) improve outcome (eg, termination of rhythm, survival) (O)? |
Unstable VT |
Jeffrey M. Berman, Bradford D. Harris |
http://circ.ahajournals.org/site/C2010/Peds-030.pdf |
| Peds |
Peds-031 |
In infants and children with supraventricular tachycardia with a pulse (P), does the use of any drug or combination of drugs (I), compared with aden-osine (C), result in improved outcomes (termination of rhythm, survival)? |
Drugs for SVT |
Ricardo A. Samson |
http://circ.ahajournals.org/site/C2010/Peds-031.pdf |
| Peds |
Peds-032 |
In infants and children with hemorrhagic shock following trauma (P), does the use of graded volume resuscitation (I) as opposed to standard care (C), improve outcome (hemodynamics, survival) (O)? |
Graded volume resuscitation for traumatic shock |
Jesus Lopez-Herce |
http://circ.ahajournals.org/site/C2010/Peds-032.pdf |
| Peds |
Peds-033 |
In pediatric patients in cardiac arrest (prehospital [OHCA], in-hospital [IHCA]) (P), does the use of one hand chest compressions (I) compared with two hand chest compressions (C) improve outcomes (eg. ROSC, rescuer performance) (O)? |
One hand vs two hand compressions |
Sharon B. Kinney |
http://circ.ahajournals.org/site/C2010/Peds-033.pdf |
| Peds |
Peds-034 |
In infants with cardiac arrest (prehospital [OHCA], in-hospital [IHCA]) (P), does the use of two-thumb chest compression without circumferential squeeze (I) compared to two-thumb chest compression with circumferential squeeze (C) improve outcome (eg. ROSC, rescuer performance (O)? |
Circumferential squeeze for infant CPR |
James Tibballs |
http://circ.ahajournals.org/site/C2010/Peds-034.pdf |
| Peds |
Peds-035 |
In infants and children with cardiac arrest (P), does establishing intraosseous access (I) compared to establishing conventional (non-intraosseous) venous access (C) improve patient outcome (eg. ROSC, survival to hospital discharge (O)? |
IO vs IV |
Jonathan Duff |
http://circ.ahajournals.org/site/C2010/Peds-035.pdf |
| Peds |
Peds-036 |
In infants and children with cardiac arrest (P), does the use of tracheal drug delivery (I) compared to intravenous drug delivery (C) worsen patient outcome (eg. ROSC, survival to hospital discharge (O)? |
ET vs IV drugs |
Mioara D. Manole |
http://circ.ahajournals.org/site/C2010/Peds-036.pdf |
| Peds |
Peds-038B |
In infants and children in shock, does early intubation and assisted ventilation compared to the use of these interventions only for associated respiratory failure lead to improved patient outcome (hemodynamics, survival?) |
Intubation for shock (timing) |
Amelia Reis |
http://circ.ahajournals.org/site/C2010/Peds-038B.pdf |
| Peds |
Peds-039A |
In infants and children with respiratory failure who require emergent endotracheal intubation (P), does the use of cricoid pressure or laryngeal manipulation (I), when compared with standard practice (C), improve or worsen outcome (eg. success of intubation, aspiration risk, side effects, etc) (O)? |
Cricoid pressure and laryngeal manipulation |
Lester T. Proctor |
http://circ.ahajournals.org/site/C2010/Peds-039A.pdf |
| Peds |
Peds-039B |
In infants and children with respiratory failure who require emergent endotracheal intubation (P), does the use of cricoid pressure or laryngeal manipulation (I), when compared with standard practice (C), improve or worsen outcome (eg. success of intubation, aspiration risk, side effects, etc) (O)? |
Cricoid pressure and laryngeal manipulation |
Ian Maconochie |
http://circ.ahajournals.org/site/C2010/Peds-039B.pdf |
| Peds |
Peds-040A |
In infants and children in cardiac arrest (out-of-hospital and in-hospital) (P), does any specific compression depth (I) as opposed to standard care (ie. depth specified in treatment algorithm) (C), improve outcome (O) (eg. Blood pressure, ROSC, survival)? |
Compression depth |
Robert M. Sutton |
http://circ.ahajournals.org/site/C2010/Peds-040A.pdf |
| Peds |
Peds-040B |
In infants and children in cardiac arrest (out-of-hospital and in-hospital) (P), does any specific compression depth (I) as opposed to standard care (ie. depth specified in treatment algorithm) (C), improve outcome (O) (eg. Blood pressure, ROSC, survival)? |
Compression depth |
David Zideman |
http://circ.ahajournals.org/site/C2010/Peds-040B.pdf |
| Peds |
Peds-041A |
In children and infants with cardiac arrest due to major (blunt or penetrating) injury (out-of-hospital and in-hospital) (P), does the use of any specific modifications to standard resuscitation (I) compared with standard resuscitation (C), improve outcome (O) (eg. ROSC, survival)? eg. open vs closed chest CPR, other examples. |
Traumatic arrest |
Kennith Sartorelli |
http://circ.ahajournals.org/site/C2010/Peds-041A.pdf |
| Peds |
Peds-041B |
In children and infants with cardiac arrest due to major (blunt or penetrating) injury (out-of-hospital and in-hospital) (P), does the use of any specific modifications to standard resuscitation (I) compared with standard resuscitation (C), improve outcome (O) (eg. ROSC, survival)? eg. open vs closed chest CPR, other examples. |
Traumatic arrest |
Jesus Lopez-Herce |
http://circ.ahajournals.org/site/C2010/Peds-041B.pdf |
| Peds |
Peds-043A |
In infants and children in cardiac arrest (prehospital [OHCA], in-hospital [IHCA]) (P), does the use of self-adhesive defibrillation pads (I) compared with paddles (C), improve outcomes (eg. successful defibrillation, ROSC, survival) (O)? |
Hands off defibrillation vs paddles |
Mark Terry |
http://circ.ahajournals.org/site/C2010/Peds-043A.pdf |
| Peds |
Peds-043B |
In infants and children in cardiac arrest (prehospital [OHCA], in-hospital [IHCA]) (P), does the use of self-adhesive defibrillation pads (I) compared with paddles (C), improve outcomes (eg. successful defibrillation, ROSC, survival) (O)? |
Hands off defibrillation vs paddles |
Farhan Bhanji |
http://circ.ahajournals.org/site/C2010/Peds-043B.pdf |
| Peds |
Peds-044A |
In infants and children with any type of shock (P), does the use of any specific resuscitation fluid or combination of fluids [eg: isotonic crystalloid, colloid, hypertonic saline, blood products] (I) when compared with standard care (C) improve patient outcome (hemodynamics, survival) (O)? |
Resuscitation fluids |
Sharon E. Mace |
http://circ.ahajournals.org/site/C2010/Peds-044A.pdf |
| Peds |
Peds-044B |
In infants and children with any type of shock (P), does the use of any specific resuscitation fluid or combination of fluids [eg: isotonic crystalloid, colloid, hypertonic saline, blood products] (I) when compared with standard care (C) improve patient outcome (hemodynamics, survival) (O)? |
Resuscitation fluids |
Richard P. Aickin |
http://circ.ahajournals.org/site/C2010/Peds-044B.pdf |
| Peds |
Peds-045A |
In infants and children with distributive shock with and without myocardial dysfunction (P), does the use of any specific inotropic agent (I) when compared to standard care (C), improve patient outcome (hemodynamics, survival) (O)? |
Distributive shock and inotropes |
Ericka L. Fink, Alfredo Misraji |
http://circ.ahajournals.org/site/C2010/Peds-045A.pdf |
| Peds |
Peds-045B |
In infants and children with distributive shock with and without myocardial dysfunction (P), does the use of any specific inotropic agent (I) when compared to standard care (C), improve patient outcome (hemodynamics, survival) (O)? |
Distributive shock and inotropes |
Loh Tsee Foong |
http://circ.ahajournals.org/site/C2010/Peds-045B.pdf |
| Peds |
Peds-046A |
In infants and children with cardiogenic shock (P), does the use of any specific inotropic agent (I) when compared with standard care (C), improve patient outcome (hemodynamics, survival) (O)? |
Cardiogenic shock and inotropes |
Akira Nishisaki |
http://circ.ahajournals.org/site/C2010/Peds-046A.pdf |
| Peds |
Peds-047A |
In infants and children with hypotensive septic shock (P), does the use of etomidate as an induction agent to facilitate intubation (I) compared with a standard technique without etomidate (C) improve patient outcome (hemo-dynamics, survival) (O)? |
Etomidate and septic shock |
Stephen M. Schexnayder |
http://circ.ahajournals.org/site/C2010/Peds-047A.pdf |
| Peds |
Peds-047B |
In infants and children with hypotensive septic shock (P), does the use of etomidate as an induction agent to facilitate intubation (I) compared with a standard technique without etomidate (C) improve patient outcome (hemo-dynamics, survival) (O)? |
Etomidate and septic shock |
Jonathan Duff |
http://circ.ahajournals.org/site/C2010/Peds-047B.pdf |
| Peds |
Peds-048A |
In infants and children who are undergoing resuscitation from cardiac arrest (P), does consideration of a channelopathy as the etiology of the arrest (I), as compared with standard management (C), improve outcome (ROSC, survival to discharge, survival with favorable neurologic outcome) (O)? |
Channelopathies |
Robert Hickey |
http://circ.ahajournals.org/site/C2010/Peds-048A.pdf |
| Peds |
Peds-048B |
In infants and children who are undergoing resuscitation from cardiac arrest (P), does consideration of a channelopathy as the etiology of the arrest (I), as compared with standard management (C), improve outcome (ROSC, survival to discharge, survival with favorable neurologic outcome) (O)? |
Channelopathies |
William Scott |
http://circ.ahajournals.org/site/C2010/Peds-048B.pdf |
| Peds |
Peds-049A |
In infants and children with hypotensive septic shock (P), does the use of corticosteroids in addition to standard care (I) when compare with standard care without the use of corticosteroids (C), improve patient outcome (eg. Hemodynamics or survival) (O)? |
Corticosteroids and septic shock |
Arno Zaritsky |
http://circ.ahajournals.org/site/C2010/Peds-049A.pdf |
| Peds |
Peds-049B |
In infants and children with hypotensive septic shock (P), does the use of corticosteroids in addition to standard care (I) when compare with standard care without the use of corticosteroids (C), improve patient outcome (eg. Hemodynamics or survival) (O)? |
Corticosteroids and septic shock |
Mark G. Coulthard |
http://circ.ahajournals.org/site/C2010/Peds-049B.pdf |
| Peds |
Peds-050A |
In infants and children with acute illness or injury (P), do specific diagnostic tests (laboratory data [mixed venous oxygen saturation, pH, lactate], (I) as opposed to clinical data (vital signs, capillary refill, mental status, end-organ function [urine output]) (C), increase the accuracy of diagnosis of shock (O)? |
Diagnostic tests for shock |
Alexis Topjian |
http://circ.ahajournals.org/site/C2010/Peds-050A.pdf |
| Peds |
Peds-050B |
In infants and children with acute illness or injury (P), do specific diagnostic tests (laboratory data [mixed venous oxygen saturation, pH, lactate], (I) as opposed to clinical data (vital signs, capillary refill, mental status, end-organ function [urine output]) (C), increase the accuracy of diagnosis of shock (O)? |
Diagnostic tests for shock |
Sharon B. Kinney |
http://circ.ahajournals.org/site/C2010/Peds-050B.pdf |
| Peds |
Peds-052A |
In infants and children with cardiac arrest or symptomatic bradycardia that is unresponsive to oxygenation and/or ventilation (P), does the use of atropine (I), as compared with epinephrine or no atropine (C), improve patient outcome (return to age-appropriate heart rate, subsequent pulseless arrest, ROSC, survival) (O)? |
Atropine vs epinephrine for bradycardia |
Susan Fuchs, Sasa Kurosawa, Masahiko Nitta |
http://circ.ahajournals.org/site/C2010/Peds-052A.pdf |
| Peds |
Peds-055B |
For infants and children with Fontan or hemi-Fontan circulation who require resuscitation from cardiac arrest or pre-arrest states (prehospital [OHCA] or in-hospital [IHCA]) (P), does any specific modification to standard practice (I) compared with standard resuscitation practice (C) improve outcome (eg. ROSC, survival to discharge, survival with good neurologic outcome (O)? |
Resuscitation for hemi-Fontan/Fontan circulation |
Desmond Bohn, Bradley S. Marino |
http://circ.ahajournals.org/site/C2010/Peds-055B.pdf |
| Peds |
Peds-056A |
For infants and children in cardiac arrest with pulmonary hypertension (prehospital [OHCA] or in-hospital [IHCA]) (P), do any specific modifications to resuscitation techniques (I) compared with standard resuscitation techniques (C), improve outcome (ROSC, survival to discharge, favorable neurologic survival) (O)? |
Resuscitation of the patient with pulmonary hypertension |
Ian Adatia, John Berger, David Wessel |
http://circ.ahajournals.org/site/C2010/Peds-056A.pdf |
| Peds |
Peds-057A |
For infants and children who require endotracheal intubation (prehospital or in hospital) (P) does the use of a specific formula to guide cuffed endotracheal tube size (I), as opposed to the use of the existing formula of 3 + age/4 (C), achieve better outcomes (eg. successful tube placement) (O)? |
Formula for cuffed ET tube size |
Robert Bingham |
http://circ.ahajournals.org/site/C2010/Peds-057A.pdf |
| Peds |
Peds-057B |
For infants and children who require endotracheal intubation (prehospital or in hospital) (P) does the use of a specific formula to guide cuffed endotracheal tube size (I), as opposed to the use of the existing formula of 3 + age/4 (C), achieve better outcomes (eg. successful tube placement) (O)? |
Formulas for predicting ET tube size |
Eugene B. Freid |
http://circ.ahajournals.org/site/C2010/Peds-057B.pdf |
| Peds |
Peds-059 |
For infants and children with single ventricle, s/p stage I repair who require resuscitation from cardiac arrest or pre-arrest states (prehospital [OHCA] or in-hospital [IHCA]) (P), does any specific modification to standard practice (I) compared with standard resuscitation practice (C) improve outcome (eg. ROSC, survival to discharge, survival with good neurologic outcome) (O)? |
Resuscitation of the patient with single ventricle |
George M. Hoffman, Shane Tibby |
http://circ.ahajournals.org/site/C2010/Peds-059.pdf |
| Peds |
Peds-060 |
For pediatric patients (in any setting (P), is there a clinical decision rule (I) that enables reliable prediction of ROSC (or futile resuscitation efforts)? (PROGNOSIS) |
Clinical decision rules to predict ROSC |
Gabrielle Nuthall |
http://circ.ahajournals.org/site/C2010/Peds-060.pdf |
