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. Author manuscript; available in PMC: 2014 Oct 1.
Published in final edited form as: Br J Haematol. 2013 Jul 25;163(1):72–80. doi: 10.1111/bjh.12498

Table I.

Combination Index values calculated for the combination treatment of chronic lymphocytic leukaemia (CLL) cells

CLL patient LBH589 SAHA
1 nM 2.5 nM 5 nM 0.5 μM 1 μM 2 μM
1 0.38 0.26 0.61 N/D 0.62 0.74
2 1.09 0.66 0.74 0.98 0.61 0.72
3 0.29 0.19 0.27 0.12 0.18 0.28
4 0.44 0.51 0.38 N/D N/D N/D
5 N/D N/D N/D 0.39 0.10 0.19

CLL, chronic lymphocytic leukaemia; LBH589, panobinostat; SAHA, suberoylanilide hydroxamic acid.