TABLE 2.

Overview of Sensitivities and Specificities in A Posteriori Simulated Double Reading Approaches (by Pairs of Radiologists) for XRM + ABUS (median [95% CI]) and the Changes with Respect to Single Reading Conditions

	XRM + ABUS Double Reading	Change wrt XRM + ABUS Single Reading	Change wrt XRM Single Reading
Aggressive
Sensitivity	71.0% [61.3%; 77.4%]	13.8% [11.2%; 17.3%]	44.4% [35.2%; 56.3%]
Specificity	79.0% [64.7%; 90.2%]	−11.6% [−12.8%; − 10.5%]	−16.7% [−18.2%; −13.3%]
Conservative
Sensitivity	48.4% [29.0%; 54.8%]	−13.9% [−17.2%; − 11.1%]	16.7% [9.1%; 26.1%]
Specificity	97.0% [95.4%; 99.3%]	11.6% [10.6%; 12.8%]	7.6% [6.0%; 9.2%]

ABUS, three-dimensional automated breast ultrasound; XRM, x-ray mammography.