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. Author manuscript; available in PMC: 2014 Jul 1.
Published in final edited form as: Arterioscler Thromb Vasc Biol. 2013 May 2;33(7):1513–1520. doi: 10.1161/ATVBAHA.113.301498

Table 2.

Mouse liver plasma membrane lipid analysis by LC/MS/MS

WT SMS2LTg WT SMS2 KO
Chow diet
PC(nmole/mg) 68±8 65±15 62±10 60±13
SM(nmole/mg) 26±7 37±6* 22±5 12±3*
Ceramide(ng/mg) 755±90 702±81 820±108 783±120
DHCer(ng/mg) 116±29 129±39 121±31 133±23
GlyCer(ng/mg) 291±42 246±35 231±52 266±44
GM3(ng/mg) 99±16 110±23 120±36 102±13
High fat diet
PC(nmole/mg) 88±11 77±21 82±9 79±14
SM(nmole/mg) 33±9 51±8* 35±6 22±5*
Ceramide(ng/mg) 937±100 902±91 990±79 883±81
DHCer(ng/mg) 144±19 121±59 129±26 124±33
GlyCer(ng/mg) 308±51 292±41 330±61 289±50
GM3(ng/mg) 120±30 99±29 116±22 105±21

Sph, sphingosine; SM, sphingomyelin; PC, phosphatidylcholine; DHCer, dihydroceramide; Glycer, Glucosylceramide. Value: mean±SD; n=4-5.

*

P<0.05.