Table 1.
Characteristics of study subjects
| ET (N = 70) | Controls (N = 27) | Statistical Test | |
|---|---|---|---|
| Age at death (years) | 86.0 ± 6.6 | 76.2 ± 15.9 | t = 3.37, p = 0.002 |
| Female gender | 43 (61.4) | 13 (48.1) | X2 = 1.41, p = 0.24 |
| Family history of tremor | 22 (31.4) | 0 (0) | Fisher’s p = 0.005 |
| Age of onset of tremor (years) | 40.5 ± 22.6 [range = 4 −85] | Not applicable | Not applicable |
| PMI 1 (hours) | 3.5 ± 3.3 [median = 2.8] | 6.0 ± 5.0 [median = 4.3] | Mann-Whitney = 2.85, p = 0.004 |
| PMI 2 (hours) | 25.3 ± 10.1 | 18.3 ± 8.9 | t = 3.14, p = 0.002 |
| Freezer time (years) | 2.4 ± 1.9 [median = 1.7] | 6.9 ± 2.75 [median = 7.9] | Mann-Whitney = 173.0, p < 0.001 |
| Brain Weight (grams) | 1179 ± 192 | 1233 ± 157 | t = 1.33, p = 0.19 |
| Braak AD Score | Fisher’s p = 0.005 | ||
| 0 – 4 | 52 (89.7) | 22 (88.0) | |
| 5 or 6 | 6 (10.3) | 3 (12.0) | |
| Braak PD Score >0 | 0 (0) | 0 (0) | X2 = 0.00, p = 1.00 |
| CERAD Score | X2 = 1.80, p = 0.05 | ||
| 0 | 21 (30.0) | 15 (55.6) | |
| A | 28 (40.0) | 9 (33.3) | |
| B | 11 (15.7) | 3 (11.1) | |
| C | 10 (14.3) | 0 (0.0) |
Values are means ± standard deviation or number (percent).
AD = Alzheimer’s Disease, CERAD = Consortium to Establish a Registry for AD, PD = Parkinson’s disease, PMI = postmortem interval.