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. 2013 Oct 1;24(19):3145–3154. doi: 10.1091/mbc.E13-05-0268

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© 2013 Li et al. This article is distributed by The American Society for Cell Biology under license from the author(s). Two months after publication it is available to the public under an Attribution–Noncommercial–Share Alike 3.0 Unported Creative Commons License (http://creativecommons.org/licenses/by-nc-sa/3.0).

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FIGURE 8: — A model for the role of Slt2p and the polarisome in ER inheritance. ER tubules are delivered into the bud by the myosin Myo4p. The tubules must be released from actin structures before they can propagate around the cortex of the bud. In ptc1∆ cells Slt2p becomes highly activated, blocking release of ER tubules from actin. This function of Slt2p requires the polarisome components Pea2p and Spa2p for its retention at the bud tip and the components Bud6p, Bni1p, and Sph1p for its activation.