Table 1. The P. falciparum genome encodes two complete FeS cluster synthesis pathways.
PATSa | PATSa | PlasmoAPa | PlasMita | |||
Pathway | Function | Gene Name (PlasmoDB) | Score | Decision | Decision | Jury (%) |
Suf | ||||||
Cysteine desulfurase | SufS (PF3D7_0716600) | .947 | api | api | Non-mito (99) | |
Cysteine desulfurase partner | SufE (PF3D7_0206100) | .977 | api | api | Non-mito (99) | |
Scaffold | SufB (PFC10_API0012)b | |||||
SufC (PF3D7_1413500) | .862 | api | Not api | Mito (91) | ||
SufD (PF3D7_1103400) | .93 | api | api | Non-mito (99) | ||
Transfer | SufU (PF3D7_0921400) | .972 | api | api | Non-mito (99) | |
SufA (PF3D7_0522700) | .951 | api | api | Non-mito (99) | ||
Isc | ||||||
Cysteine desulfurase | IscS (PF3D7_0727200) | .046 | Not api | Not api | Mito (91) | |
Cysteine desulfurase partner | Isd11 (PF3D7_1311000) | .025 | Not api | Not api | Mito (91) | |
Scaffold | IscU1 (PF3D7_1454500) | .049 | Not api | Not api | Mito (91) | |
IscU2 (PF3D7_0930900) | .468 | Not api | Not api | Mito (91) | ||
Transfer | IscA1 (PF3D7_0207200) | .119 | Not api | Not api | Mito (91) | |
IscA2 (PF3D7_0322500) | .055 | Not api | Not api | Mito (91) |