Table 2. Sensitivity, specificity, negative and positive predictive values of the DiaMed IT-LEISH and the Signal KA for VL diagnosis in Kacheliba and Kimalel, Rift Valley province, Kenya.
Index test result | VL case | Non-VL case | Sensitivity | Specificity | PPV | NPV | |
(N total = 131) | (N total = 88) | % [95% CI] | % [95% CI] | % [95% CI] | % [95% CI] | ||
Individual tests | |||||||
DiaMed IT Leish | Positive | 117 | 9 | 89.3 | 89.8 | 92.9 | 84.9 |
[82.7 to 94.0] | [81.5 to 95.2] | [86.9 to 96.7] | [76.0 to 91.5] | ||||
Negative | 14 | 79 | |||||
Signal KA | Positive | 101 | 4 | 77.1 | 95.5 | 96.2 | 73.7 |
[68.9 to 84.0] | [88.7 to 98.7] | [90.5 to 98.9] | [64.6 to 81.5] | ||||
Negative | 30 | 84 |
Abbreviations: PPV = positive predictive value, NPV = negative predictive value, CI = Confidence Interval.