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. 2013 Sep 16;123(10):4502–4512. doi: 10.1172/JCI69884

Figure 6. Human hypertensive arteries overexpress P311.

Figure 6

(A) Real-time PCR showing mRNA levels of P311 in aortas from normotensive (NT) and hypertensive (HT) patients (n = 5 per group). (B) P311 immunoreactivity (brown staining) in hernia sac arteries from 18 normotensive and 21 hypertensive patients. Scale bar: 50 μm. Quantified P311 signal intensity is also shown. (C) TGF-β immunoreactivity (brown staining) in hernia sac arteries from 18 normotensive and 21 hypertensive patients. Quantified TGF-β signal intensity is also shown. Original magnification, ×25. (D) Smad2/3 immunoreactivity (brown staining) in hernia sac arteries from normotensive and hypertensive patients. Original magnification, ×100. The number of positive Smad2/3 nuclei is also shown. Data represent mean ± SD. **P < 0.01, 1-way ANOVA.