Effects of cdk10 depletion on neurogenesis on the basis of the Tg (huC:gfp) model. Embryos that received the indicated MO were collected at 24 (A and B) and 48 HPF (C and D). A, the huC expression in the telencephalon decreased in cdk10 morphants. Reduced numbers of RB neurons were also observed in cdk10 morphants. C and D, the cdk10 morphants exhibited abrogated huC expression in the forebrain region and a significantly decreased huC population of neurons in the retina. A–C, lateral view. Scale bars, 100 μm. Ctrl, control.