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. 2013 Jul 29;288(39):27972–27985. doi: 10.1074/jbc.M113.477547

TABLE 4.

PrPSc aggregation ratio for each CJD type

The aggregation ratio is expressed as mean ± S.D. Statistical significance was evaluated by means of one-way ANOVA followed by pairwise multiple comparisons carried out by the Holm-Sidak method. Statistically significant comparisons included VPSPr versus MM 2T, versus vCJD, versus VV2 (p < 0.001), and versus MV 2K (p = 0.001); VV1 versus MM 2T, versus vCJD (p < 0.001), and versus VV2 (p = 0.001); MM 2C versus MM 2T and versus vCJD (p < 0.001); and MM1 versus MM 2T and versus vCJD (p < 0.001).

CJD type Sample size (n) Aggregation ratio
VPSPr 2 3.76 ± 0.28
VV1 6 5.47 ± 0.46
MM 2C 5 5.68 ± 0.99
MM1 6 6.43 ± 2.15
MV 2K 6 8.38 ± 1.93
VV2 6 8.68 ± 1.22
MM 2T 4 10.92 ± 1.44
vCJD 3 11.65 ± 3.35