TABLE 4.
PrPSc aggregation ratio for each CJD type
The aggregation ratio is expressed as mean ± S.D. Statistical significance was evaluated by means of one-way ANOVA followed by pairwise multiple comparisons carried out by the Holm-Sidak method. Statistically significant comparisons included VPSPr versus MM 2T, versus vCJD, versus VV2 (p < 0.001), and versus MV 2K (p = 0.001); VV1 versus MM 2T, versus vCJD (p < 0.001), and versus VV2 (p = 0.001); MM 2C versus MM 2T and versus vCJD (p < 0.001); and MM1 versus MM 2T and versus vCJD (p < 0.001).
CJD type | Sample size (n) | Aggregation ratio |
---|---|---|
VPSPr | 2 | 3.76 ± 0.28 |
VV1 | 6 | 5.47 ± 0.46 |
MM 2C | 5 | 5.68 ± 0.99 |
MM1 | 6 | 6.43 ± 2.15 |
MV 2K | 6 | 8.38 ± 1.93 |
VV2 | 6 | 8.68 ± 1.22 |
MM 2T | 4 | 10.92 ± 1.44 |
vCJD | 3 | 11.65 ± 3.35 |