FIGURE 7.

Differences of angiogenic related protein expression between RAC exosomes and RPE exosomes. Exosome extracts of RPE and RACs were incubated with angiogenesis antibody array according to the manufacturer's instructions. A, the numbers are indicated as differences in the expression of proteins between RAC and RPE exosomes. These are 1, endostatin; 2, ET-1; 3, KC; 4, MIP-1α; 5, MMP-3; 6, MMP-9; 7, NOV; 8, PTX3; 9, PlGF-2; 10, proliferin; 11, PEDF; and 12, TIMP-1. B, graphs represent quantification of antibody array using ImageJ software (National Institutes of Health). C, the levels of endostatin and PEDF in exosomes of RAC and RPE were quantitated by ELISA.