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. 2013 Aug 7;288(39):28138–28151. doi: 10.1074/jbc.M113.499640

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© 2013 by The American Society for Biochemistry and Molecular Biology, Inc.

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FIGURE 5. — The H2 relaxin-induced cAMP response of L7K-RXFP1 and L7A-RXFP1 (A) and L7K-RXFP1, L7A-RXFP1, L7K/L22K-RXFP1, and L7A/L22A-RXFP1 (B) is shown. C, Y9F-RXFP1, Y9M-RXFP1, and L7K/Y9M-RXFP1 compared with RXFP1. cAMP activity is expressed as the percentage of the 5 μm forskolin-stimulated response for each receptor and has been normalized for cell surface expression. Symbols represent means and vertical bars represent S.E. of triplicate determinations from at least three independent experiments.