Figure 8.
Summary of significant mRNA and protein expression for γ-aminobutyric acid A and B (GABAA and GABAB) receptors in the lateral cerebella of subjects with major depression. Increased expression of GABRα1 protein may lead to a negative feedback loop decreasing the mRNA expression. ↑, increased expression; ↓, reduced expression, --, no change. GABAB receptor subunits 1 and 2 (GABBR1 and GABBR2) data reprinted from Fatemi et al.,29 with permission from Elsevier.