Table 2. Haplotype frequencies of the 5-HTTLPR and rs25531 polymorphisms.
|
Haplotype groups by high/low transcriptiona |
||||||
|---|---|---|---|---|---|---|
| 5-HTTLPR/rs25531 haplotype | EA | AA | Test of difference | EA | AA | Test of difference |
| L-A | 0.50 | 0.52 | χ2=115.32, df=5, P=0.0001 | 0.50 | 0.53 | χ2=4.7838, df=1, P=0.03 |
| xL-A | 0.0006 | 0.01 | ||||
| L-G | 0.07 | 0.21 | ||||
| S-A | 0.43 | 0.25 | ||||
| S-G | 0.005 | 0.001 | ||||
| xL-G | 0.0004 | 0.002 | 0.50 | 0.46 | ||
Abbreviations: AA, African American; EA, European American; L, long allele; S, short allele.
a
Not bold rows indicate a high-transcription group and bold rows display a low-transcription group.