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. 2013 Sep 19;3(5):408–416.

Table 3.

This shows the sensitivity and specificity of PET/CT versus non-contrast CT in monitoring for recurrence 1 year after lobectomy for clinical stage 1 NSCLC. Table 3A shows the sensitivity of PET/CT and non-contrast CT for all patients included in this study. For all patients included in this study, PET/CT is more sensitive than non-contrast CT alone in monitoring for recurrence 1 year after lobectomy.Table 3B compares the sensitivity of PET/CT and non-contrast CT for the subset of patients confirmed to have stage 1 NSCLC after surgery. For these patients, there was no difference in the sensitivity of PET/CT and non-contrast CT in monitoring for recurrence. Table 3C shows the sensitivity and specificity of PET/CT and non-contrast CT monitoring for recurrence in the subset of patients upstaged to stage 2 or 3 after surgery. PET/CT is more sensitive than non-contrast CT in monitoring for recurrence in this subset of patients. There was no statistically significant difference in the specificity of PET/CT and non-contrast CT in all subsets of patients.

A. All pathologic stages, clinical stage 1

CT PET/CT CT Relative to PET/CT

Sensitivity (%) 56.3 100 56.3 (p = 0.016, 95% CI: 37-87)
Specificity (%) 96 93.2 103 (p = 0.62, 95% CI: 22-165)

B. Pathologic Stage 1

CT PET/CT CT Relative to PET/CT

Sensitivity (%) 83.3 100 83.3 (p = 0.31, 95% CI: 52-124)
Specificity (%) 95.2 93.7 102 (p = 0.56, 95% CI: 15.7-188)

C. Pathologic Stage 2/3

CT PET/CT CT Relative to PET/CT

Sensitivity (%) 40 100 40 (p = 0.03, 95% CI: 18.7-85.4)
Specificity (%) 100 90.9 110 (p = 0.31, 95% CI: 58.8-285)