Table 3.
This shows the sensitivity and specificity of PET/CT versus non-contrast CT in monitoring for recurrence 1 year after lobectomy for clinical stage 1 NSCLC. Table 3A shows the sensitivity of PET/CT and non-contrast CT for all patients included in this study. For all patients included in this study, PET/CT is more sensitive than non-contrast CT alone in monitoring for recurrence 1 year after lobectomy.Table 3B compares the sensitivity of PET/CT and non-contrast CT for the subset of patients confirmed to have stage 1 NSCLC after surgery. For these patients, there was no difference in the sensitivity of PET/CT and non-contrast CT in monitoring for recurrence. Table 3C shows the sensitivity and specificity of PET/CT and non-contrast CT monitoring for recurrence in the subset of patients upstaged to stage 2 or 3 after surgery. PET/CT is more sensitive than non-contrast CT in monitoring for recurrence in this subset of patients. There was no statistically significant difference in the specificity of PET/CT and non-contrast CT in all subsets of patients.
| A. All pathologic stages, clinical stage 1 | |||
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| CT | PET/CT | CT Relative to PET/CT | |
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| Sensitivity (%) | 56.3 | 100 | 56.3 (p = 0.016, 95% CI: 37-87) |
| Specificity (%) | 96 | 93.2 | 103 (p = 0.62, 95% CI: 22-165) |
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| B. Pathologic Stage 1 | |||
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| CT | PET/CT | CT Relative to PET/CT | |
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| Sensitivity (%) | 83.3 | 100 | 83.3 (p = 0.31, 95% CI: 52-124) |
| Specificity (%) | 95.2 | 93.7 | 102 (p = 0.56, 95% CI: 15.7-188) |
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| C. Pathologic Stage 2/3 | |||
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| CT | PET/CT | CT Relative to PET/CT | |
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| Sensitivity (%) | 40 | 100 | 40 (p = 0.03, 95% CI: 18.7-85.4) |
| Specificity (%) | 100 | 90.9 | 110 (p = 0.31, 95% CI: 58.8-285) |