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. Author manuscript; available in PMC: 2014 Aug 2.
Published in final edited form as: J Proteome Res. 2013 Jun 27;12(8):3697–3706. doi: 10.1021/pr400321x

Figure 1. Effects of AUY922 on cultured Jurkat leukemia cells.

Figure 1

Panel 1A, Cell proliferation after 24, 48, or 72 hr incubation in the presence of the indicated concentrations of AUY922 (n=3). Panel 1B, Cdk6 levels after 0–8 hr of treatment with 150 nM 17-DMAG. Panel 1C, Cdk6 levels after 24 hr of treatment with the indicated concentrations of AUY922. Panel 1D, Densitometry of Cdk6 levels remaining after 24 hr of treatment with the indicated concentrations of AUY922 (n=3). Panel 1E, PARP cleavage after 24 treatment with the indicated concentrations of AUY922.