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. Author manuscript; available in PMC: 2014 Aug 2.
Published in final edited form as: J Proteome Res. 2013 Jun 27;12(8):3697–3706. doi: 10.1021/pr400321x

Figure 10. AZC-induced protein folding burdens potentiate AUY922’s inhibition of cellular proliferation.

Figure 10

Jurkat cultures were pre-treated for 10 hr with indicated concentrations of AZC, followed by treatments with indicated concentrations of AUY922. After 38 hr additional incubation (48 hr total), metabolic activity was measured as described in Methods. Results show the averages and SEM from three independent biological replicates. Asterisks denote statistically significant differences in proliferation ( p < 0.05, *; p < 0.01, **; p < 0.001, ***).