Table 3.
Invasive colorectal cancer outcomes (annualized%) for White and African American women
| Model 1a |
Model 2b |
|||||
|---|---|---|---|---|---|---|
| N (Annualized%) | HR (95% CI) | HR (95% CI) | ||||
| Proximal invasive colorectal cancer | ||||||
| White | 882 | (0.06%) | 1.00 | 1.00 | ||
| African–American | 103 | (0.07%) | 1.25 | (1.02, 1.54) | 1.18 | (0.91, 1.51) |
| P-value c | 0.03 | 0.21 | ||||
| Distal invasive colorectal cancer | ||||||
| White | 403 | (0.03%) | 1.00 | 1.00 | ||
| African–American | 46 | (0.03%) | 1.07 | (0.79, 1.46) | 0.96 | (0.64, 1.42) |
| P-value c | 0.66 | 0.83 | ||||
| Invasive rectal canced | ||||||
| White | 318 | (0.02%) | 1.00 | 1.00 | ||
| African–American | 34 | (0.02%) | 0.99 | (0.69, 1.41) | 0.70 | (0.43, 1.12) |
| P-value c | 0.95 | 0.13 | ||||
| Death from colorectal cancer | ||||||
| White | 411 | (0.03%) | 1.00 | 1.00 | ||
| African–American | 51 | (0.04%) | 0.92 | (0.69, 1.24) | 0.78 | (0.53, 1.13) |
| P-value c | 0.59 | 0.18 | ||||
a
Adjusted for age and stratified on WHI trial and extension study participation.
b
Adjusted for age, education, diabetes, body mass index, physical activity, smoking, alcohol use, NSAID use, total dietary energy, dietary fiber, red meat, fruits and vegetables, total calcium intake, prior colon screening, history of colon polyp removal, family history of colorectal cancer, and prior menopausal hormone use and stratified on WHI trial and extension study participation.
c
P-value is from a Wald χ2 test for the main effect of race/ethnicity.
d
Includes rectum and rectosigmoid junction sites.