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. 2000 Jun 15;105(12):1697–1710. doi: 10.1172/JCI7739

Figure 9.

Figure 9

Effects of Ad5E1mIL-4 on osteoclast-like cells. (a–d) Arthritic knee joint of a mouse 7 days after intra-articular injection of 1.107 pfu of Ad5del70-3 control vector. Note the TRAP-positive mononuclear cells in the erosive front (red). (e–h) Knee joint of a mouse 7 days after intra-articular injection of 1.107 pfu of Ad5E1mIL-4. Note the decreased number of TRAP-positive mononuclear cells. e, ×100. a–d and f–h, ×200. P, patella; F, femur; JS, joint space; C, cartilage; S, synovium; CB, cortical bone; TP, tibia plateau.