Table 1.
Variable | No Aspirin at Discharge | Aspirin at Discharge | Overall P Value | Discharge Aspirin P Value | In‐Hospital ASA P Value | ||
---|---|---|---|---|---|---|---|
No Aspirin in Hospital (n =679) | Aspirin in Hospital (n =197) | No Aspirin in Hospital (n =83) | Aspirin in Hospital (n =669) | ||||
Age, y | 65.0 (15.8) | 64.4 (15.4) | 63.9 (12.8) | 65.6 (13.1) | 0.61 | 0.44 | 0.51 |
Male gender | 360 (53%) | 113 (57%) | 57 (69%) | 441 (66%) | <0.001 | <0.001 | <0.001 |
Diabetes | 85 (13%) | 39 (20%) | 11 (13%) | 133 (20%) | 0.01 | 0.01 | <0.001 |
Hypertension | 315 (46%) | 103 (52%) | 36 (43%) | 355 (53%) | 0.05 | 0.09 | 0.01 |
SBP, mm Hg | 150.5 (29.6) | 151.9 (27.8) | 157.5 (30.7) | 155.3 (26.2) | 0.01 | <0.001 | 0.02 |
Cholesterol (highest prior to admission), mg/dL | 261.2 (63.4) | 255.3 (57.0) | 267.5 (49.8) | 272.3 (63.5) | <0.001 | <0.001 | 0.04 |
Family history | 160 (24%) | 51 (26%) | 25 (30%) | 206 (31%) | 0.02 | 0.01 | 0.01 |
Prior aspirin | 34 (5%) | 47 (24%) | 27 (33%) | 217 (32%) | <0.001 | <0.001 | <0.001 |
Prior revascularization | 47 (7%) | 25 (13%) | 19 (23%) | 130 (19%) | <0.001 | <0.001 | <0.001 |
History of prior MI or CAD | 314 (46%) | 89 (45%) | 49 (59%) | 358 (54%) | 0.01 | 0.01 | 0.11 |
ST‐segment depression ≥ 1 mm | 41 (6%) | 27 (14%) | 4 (5%) | 67 (10%) | 0.01 | 0.23 | <0.001 |
Extracardiac vascular disease | 30 (4%) | 10 (5%) | 3 (4%) | 37 (6%) | 0.75 | 0.48 | 0.31 |
Pulmonary edema, related to ischemia | 45 (7%) | 16 (8%) | 4 (5%) | 45 (7%) | 0.78 | 0.72 | 0.62 |
Ever smoked | 382 (56%) | 115 (59%) | 52 (63%) | 411 (61%) | 0.25 | 0.05 | 0.12 |
AHCPR risk category | 0.04 | 0.05 | 0.01 | ||||
High risk | 148 (22%) | 53 (27%) | 18 (22%) | 143 (21%) | |||
Inter risk | 447 (66%) | 126 (64%) | 58 (70%) | 504 (75%) | |||
Low risk | 84 (12%) | 18 (9%) | 7 (8%) | 22 (3%) |
Abbreviations: AHCPR, Agency for Health Care Policy and Research; ASA, aspirin; CAD, coronary artery disease; MI, myocardial infarction; SBP, systolic blood pressure. Numbers in table represent mean (standard deviation) or no (%)