Table 4.
Conditional model including study type in analyses of antidepressant response and remission rates.
Response
| ||||
---|---|---|---|---|
Fixed Effect | Coefficient | se | t ratio | p value |
Intercept | −0.096 | 0.074 | −1.30 | 0.198 |
Comparator | 0.59 | 0.88 | 6.77 | < 0.001 |
| ||||
Random Effect | Variance Component | df | χ2 | p value |
| ||||
Intercept | 0.136 | 85 | 503.20 | < 0.001 |
| ||||
Remission
| ||||
Fixed Effect | Coefficient | se | t ratio | p value |
| ||||
Intercept | −0.959 | 0.266 | −3.610 | 0.001 |
Comparator | 0.710 | 0.302 | 2.348 | 0.025 |
| ||||
Random Effect | Variance Component | df | χ2 | p value |
| ||||
Intercept | 0.180 | 32 | 277.831 | < 0.001 |
‘Comparator’ = dummy variable coded ‘1’ for comparator trials and ‘0’ for placebo-controlled trials. ‘Intercept’ reflects reference category of placebo-controlled trials.