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. Author manuscript; available in PMC: 2013 Sep 27.
Published in final edited form as: Pediatr Infect Dis J. 2013 Jan;32(1):78–83. doi: 10.1097/INF.0b013e3182783dc3

TABLE 1.

Summary-of-findings Table on Mortality and Omphalitis

Illustrative Comparative Risks
Outcomes Assumed Risk
Corresponding Risk
Relative Effect
 (95% CI)
No. of Participants
 (Studies)
 Quality of the
Evidence (GRADE)
Comments
Dry Care Antimicrobials
Neonatal mortality number
 of deaths within 28 d
26 per 1000 23 per 1000 (21–26) RR 0.88 (0.79–0.99) 44,818 (3 studies) ⊕⊕⊕⊕ high*
Follow-up: mean 28 d
Omphalitis number of
 omphalitis cases
108 per 1000 84 per 1000 (81–88) RR 0.78 (0.75–0.81) 44,600 (3 studies) ⊕⊕⊕⊕⊖ moderate*
Follow-up: mean 28 d

Antimicrobials compared with dry care for umbilical cord care.

Patient or population: patients with umbilical cord care

Settings: community

Intervention: antimicrobials

Comparison: dry care

GRADE Working Group grades of evidence

High quality: Further research is very unlikely to change our confidence in the estimate of effect.

Moderate quality: Further research is likely to have an important impact on our confidence in the estimate of effect and may change the estimate.

Low quality: Further research is very likely to have an important impact on our confidence in the estimate of effect and is likely to change the estimate.

Very low quality: We are very uncertain about the estimate.

*

Study setting: Asia.