Table 2.

Tamoxifen and metabolite concentrations in different age groups

Age (years)	Tamoxifen	4OHtam	4OHNDtam	NDtam	NDDtam	TamNox
30–49 (n = 33)
Median (ng/ml)	75	5.5	44	187	26	7.8
Range (min–max)	176 (27–203)	9.5 (1.7–11.3)	65 (24–89)	473 (90–563)	77 (11–89)	19 (2.7–21.2)
50–69 (n = 83)
Median (ng/ml)	95	5.8	51	229	38	9.5
Range (min–max)	271 (31–302)	10 (2.8–13.0)	116 (25–141)	575 (116–691)	78 (16–93)	34 (3.5–38.0)
>69 (n = 35)
Median (ng/ml)	96	5.5	54	255	42	10
Range (min–max)	188 (36–224)	15 (2.2–17)	159 (26–185)	415 (97–512)	72 (18–90)	21 (3.9–25)