Table 1.
Electrolyte profile of wild-type and slc26a6−/− mice urine
Variable | Slc26a6+/+ | Slc26a6−/− | P Value | ||
---|---|---|---|---|---|
Mean ± SEM | Urine Samples (n) | Mean ± SEM | Urine Samples (n) | ||
Citrate (mg/24 hr) | 0.45±0.07 | 18 | 0.14±0.03 | 18 | <0.05 |
Oxalate (mg/24 hr) | 0.06±0.01 | 18 | 0.18±0.03 | 18 | <0.05 |
Total volume (ml/24 hr) | 1.6±0.16 | 18 | 1.6±0.19 | 18 | NS |
pH | 6.2±0.07 | 18 | 6.07±0.04 | 18 | NS |
Creatinine (mg/24 hr) | 0.74±0.05 | 18 | 0.65±0.06 | 18 | NS |
Ca2+ (mg/24 hr) | 0.12±0.02 | 18 | 0.06±0.01 | 18 | <0.05 |
Mg2+ (mg/24 hr) | 0.36±0.04 | 18 | 0.46±0.04 | 17 | NS |
Cl-(mEq/24 hr) | 0.26±0.02 | 17 | 0.22±0.02 | 16 | NS |
NH4+(mEq/24 hr) | 0.08±0.01 | 18 | 0.09±0.01 | 18 | NS |
SO42− (mmol/24 hr) | 0.05±0.01 | 18 | 0.05±0.01 | 18 | NS |
Urine samples were collected in 3 consecutive days from six mice from each group and analyzed for the listed electrolytes and metabolites. NS, not significant.