Table 3.

Prognostic performance of pretransplant assays of cellular immunity to CMV

Variable	c-Statistic	Cut-off (Percentage IFN-γ–Releasing Cells)	Sensitivity	NPV	Specificity	PPV
D−R+ transplantation
IE-1 (CD8)	0.76	0.16	0.83	0.86	0.50	0.45
pp65 (CD4)	0.54	0.40	1.00	1.00	0.08	0.35
D+R+ transplantation
IE-1 (CD8)	0.56	0.82	0.67	0.50	0.38	0.55
pp65 (CD4)	0.52	0.05	0.56	0.50	0.50	0.56

Endpoint of CMV infection during first 12 months after transplantation. NPV, negative predictive value; PPV, positive predictive value.