Table 3.
Variable | Univariate HR (95%CI) | Multivariable HR (95%CI) |
---|---|---|
Treatment arm | 1.86 (1.09–3.16) | NA |
Initial sputum smear | ||
Negative or <2+ AFB | 1.0 (referent) | 1.0 (referent) |
High bacillary load ( AFB) | 2.74 (1.61–4.66) | 1.95 (1.14–3.34) |
Cavity on CXR | ||
None | 1.0 (referent) | 1.0 (referent) |
Cavity on early CXR, resolved | 3.01 (1.42–6.40) | 2.23 (1.04–4.79) |
Persistent cavity on EOT CXR | 7.23 (3.52–14.85) | 4.81 (2.31–10.03) |
White race | 2.53 (1.49–4.31) | 2.24 (1.31–3.81) |
Underweight | 4.13 (2.44–6.98) | 3.19 (1.88–5.42) |
HR = hazard ratio; CI = confidence interval; NA = not available; AFB = acid-fast bacilli; CXR = chest radiograph; EOT = end of treatment.